Management of occult papillary thyroid cancer found incidentally during surgery for benign disease.

1. Lang W, Borrusch H, Bauer L. Occult carcinoma of the thyroid. Evaluation of 1,020 sequential autopsies. Am J Clin Pathol 1988;90:72-6. 2. Rosai J, LiVolsi VA, Sobrinho-Simoes M, Williams ED. Renaming papillary microcarcinoma of the thyroid gland: The Porto proposal. Int J Surg Pathol 2003;11:249-51. 3. Lin DJ, Huang BY, Chao TC, Hsueh C. Diagnosis of occult thyroid carcinoma by thyroid ultrasonography with fine needle aspiration cytology. Acta Cytol 1997;41:1751-6. 4. Pennelli N, Pennelli G, Merante Boschin I, Pelizzo MR. Thyroid intrafollicular neoplasia (TIN) as a precursor of papillary microcarcinoma. Ann Ital Chir 2005;76:219-24. 5. Sakorafas GH, Stafyla V, Kolettis T, Tolumis G, Kassaras G, Peros G. Microscopic papillary thyroid cancer as an incidental finding in patients treated surgically for presumably benign thyroid disease. J Postgrad Med 2007;53:23-6. 6. Fischer AH, Pennelli G, Merante Boschin I, Pelizzo MR. Papillary thyroid carcinoma oncogene (RET/PTC) alters the nuclear envelope and chromatin structure. Am J Pathol 1998;153:1443-50. 7. Borrello MG, Alberti L, Fischer A, Degl’innocenti D, Ferrario C, Gariboldi M, et al. Induction of a proinflammatory program in normal human thyrocytes by the RET/PTC1 oncogene. Proc Nat Acad Sci USA 2005;102:14825-30. 8. Gasbarri A, Sciacchitano S, Marasco A, Papotti M, Di Napoli A, Marzullo A, et al. Detection and molecular characterisation of thyroid cancer precursor lesions in a specific subset of Hashimoto’s thyroiditis. Br J Cancer 2004;91:1096-104. 9. Magro G, Torrisi A, Ippolito O, Torrisi A, Bisceglia M. Unusual nonneoplastic lesions in the “surgical pathology” of the thyroid. Patologica 2006;98:119-38.